Herschel catalogued it as nebula 3334 in his Results of Astronomical Observations made at the Cape of Good Hope, published in 1847.
Strong ultraviolet radiation and stellar winds have cleared the gas and dust, giving an unobscured view of the cluster.
[8] NGC 3603 is visible in the telescope as a small rather insignificant nebulosity with a yellowish tinge due to the effects of interstellar absorption.
NGC 3603 is now considered to be such a region, and it has been compared by some authors to the larger cluster 30 Doradus, in the Large Magellanic Cloud.
WR 42e is a possible runaway from a three-body encounter, while MTT 58 appears to still be embedded within its parental cocoon and is in a possible binary with an O3If star.