It is the corporation's second radio station, and is known for broadcasting classical music.

The station was initially simply referred to as "Segundo Programa".

Launched in November 1965 as the "Segundo Programa" (second programme) of RNE – and subsequently known as "RNE 2" (1988–94), later still as "RNE C" (1994–99) – Radio Clásica's schedule is made up of presenter-led programmes of classical music (in the widest sense) plus relays (both live and recorded) of concerts, other musical recitals, and complete operas.

The station also showcases such genres as flamenco, folk music, zarzuela and jazz, as well as "established" popular music.

It is unusual amongst Spanish radio stations in including no news bulletins in its schedules.