Named Bishop of Xalapa in 1919, he was driven out of his diocese and forced to live the remainder of his life in hiding in Mexico City.

Guízar lived several times without a home and hid his priestly work under disguises as a street seller, a musician, and a doctor of homeopathic medicine, which allowed him to administer the sacraments in secrecy.

In 1920, he participated in relief and recovery efforts for survivors and towns badly affected by an earthquake which struck Veracruz in January.

[4] In December 1937, while on a mission in Cordoba, he suffered a heart attack and died on 6 June 1938 in Mexico City.

[7] In April 2006, Pope Benedict XVI confirmed a miracle that happened through the intercession of the Blessed, which opened the way to canonisation in 2006.