He played in Major League Baseball (MLB) for the Seattle Mariners, Atlanta Braves, Tampa Bay Rays, New York Yankees, Washington Nationals, and Chicago Cubs.

However, his mother, Magali, who worked as a housekeeper, often could not afford the twenty dominican pesos it cost for him to make the trip.

[1] Soriano was not well connected to Dominican trainers, who fed information to the most prominent Major League Baseball scouts.

Soriano attended the Dominican baseball academy of the St. Louis Cardinals at the age of 16, but they opted not to sign him.

A friend told Soriano that he had signed a contract with the Hiroshima Carp, a team in the Central League of Nippon Professional Baseball, which had a Dominican academy in San Pedro de Macorís.

Soriano refused to falsify his documents, and he left the Carp training facility, returning to work.

[1] Ramón de los Santos, working as a scout for the Seattle Mariners, received a tip from an acquaintance about Soriano.

[2] Heading into spring training in 1999, Soriano prepared himself for the possibility that Seattle would release him, at which point he planned to return to the Dominican Republic to work.

[2] For Everett, Soriano recorded 83 strikeouts and a team-leading 3.11 earned run average (ERA) in 75+1⁄3 innings pitched.

After an effective 2003 season, Soriano suffered a torn ulnar collateral ligament in his right elbow, and underwent Tommy John surgery on August 17, 2004.

Soriano suffered a concussion on August 29, 2006, after being struck behind the ear by a line drive hit from Angels slugger Vladimir Guerrero.

[15][16] Soriano was traded to the Atlanta Braves from the Mariners on December 7, 2006, for left-handed pitcher Horacio Ramírez.

Soriano had a mixed bag of success and disappointment in his first season in Atlanta, primarily serving as the setup man to closer Bob Wickman.

[20] That offseason, the Braves offered Soriano arbitration, expecting that he would decline and test free agency.

[21] Soriano won the Delivery Man of the Month Award for May 2010,[22] and July 2010, becoming the first pitcher to earn that honor twice in one season.

[32] On July 30, Soriano pitched his first game since coming off the DL, throwing a scoreless 9th inning, striking out 2 in a 17–3 blowout win vs. the Baltimore Orioles.

After Rivera was injured for the 2012 season shagging fly balls at Kauffman Stadium in Kansas City, Robertson was slated for the closer role and Soriano the 8th.

[33] On January 15, 2013, Soriano and the Washington Nationals agreed to a $28 million, two-year contract, pending a physical.

On February 28, 2016, Soriano signed a minor league contract with an invite to spring training with the Toronto Blue Jays.