The railway greatly assisted in the building of Panama Canal, which closely paralleled and in some places took over the rail line.
In 1914, a contract was signed for construction of a railroad David - Boquete - Concepción with a branch Dolega - Potrerillos and another short one to Puerto Pedregal.
[3] Edwards Rail Car company reports an undated acknowledgment of their three railcars,[4] which were delivered to Ferrocarril de Chiriquí probably in the 1920s.
After 1974, the infrastructure of Chiriquí Railroads was transferred to Ministry of Public Works (Ministerio de Obras Públicas) and operations were stopped around 1990.
[5] At the beginning of the twenty-first century, the tracks of the defunct railroads were being dismantled and reused for construction of bridges in rural areas.
[7] Rehabilitation of the depot and the rolling stock located at La Concepción for a new museum began in January 2021.
[5] The northern, in Bocas del Toro Province, covered Almirante, Changuinola, Guabito and parts of Sixaola.
There have been proposals for a tramway system to supplement the Panama City Metro, but as of 2022 no construction has taken place.
[12] The project, favored by president Juan Carlos Varela, was cancelled by September 2019 by his successor Laurentino Cortizo.