[2] He is noted for his rough voice and alopecia universalis, which he claims was the result of coming into contact with industrial waste during a stunt sequence.
He played a small but significant role in Pithamagan (2003) and made his full-fledged acting debut as a villain in Naan Kadavul (2009).
[2][5] His appearance as a killer who dons the garb of a woman in Thirudan Police (2014) was appreciated by critics as "the ultimate showstealer and his already popular lady makeover clinches it big time".
[5] The Times of India wrote, "His bald head, thin figure and sandpapery voice make him effective for both villainous and comical roles but from the screams and whistles that his character gets, it is clear that he has made much more impact as a comedian".
Before its release, Rajendran's presence in the film's promotional videos received a positive response.