His work has led to new techniques for fabricating and manipulating materials at the nano scale level, including functional device structures for microelectronics, optics and chemical sensing.
Nuzzo was a pioneer in the development of methods of self-assembled monolayers[1] that have led to entirely new areas of surface chemistry with important extensions into physics, biology and materials, and with numerous applications ranging from bio-sensors to advanced electronics.
His work has made important contributions to soft lithography – a low cost alternative to conventional photo-lithography for patterning circuits on microchips.
Nuzzo co-authored the paper on the "use of principles of physical organic chemistry to create functional surfaces based on self-assembled monolayers (SAMs)."
After completing his graduate studies, he accepted a position at Bell Laboratories, then a part of AT&T, where he held the title of distinguished member of the technical staff in materials research.