Ralph Smith O'bré (died August 1820) was an Irish physician who was the president of the Royal College of Surgeons in Ireland (RCSI) in 1790.
Charles Cameron wrote in his history of the RCSI that the place was either Clantilow or Lisburn and that he was the second son of Edward Obre, of Clantilow (present day Loughgall), County Armagh, and his wife, Frances Smith, of Lisburn.
[2] O'bré served an apprenticeship with his brother-in-law Samuel Croker-King and was an army surgeon in the Irish establishment.
He followed Philip Woodroffe as College treasurer, a position he held for 27 years, but he resigned in 1820 on the grounds of ill-health.
He was secretary to the Infirmaries' Board for several years[2] and he was president of the Royal College of Surgeons in Ireland in 1790.