He was a member of the Congress of Deputies and the City Council of Madrid in the early years after the Spanish transition to democracy.
In 2023, aged 89, he was proposed as a candidate for prime minister of Spain in a vote of no confidence tabled by Vox.
The PCE formed a pact with the Spanish Socialist Workers' Party (PSOE), whose leader Enrique Tierno Galván became mayor and Tamames his first deputy.
He quit the PCE in 1981 due to disputes with leader Santiago Carrillo, and in 1984 he established the Progressive Federation (FP).
[2] In February 2023, aged 89, Tamames put himself forward to be an independent candidate for prime minister if a Vox-proposed motion of no confidence in the government of Pedro Sánchez were successful.