[2] Bradley attended Manhattan Park West High School in New York City under coach Abram White, where he averaged 20.0 points, 8.0 rebounds and 6.0 assists per game as a senior.

He was then offered a scholarship to play at Kentucky, and was part of the recruiting class that included All-Americans Rajon Rondo, Joe Crawford, and Randolph Morris.

On June 28, 2009, Ramel Bradley signed with a French PRO-A team JDA Dijon.

He played the entire 2009–2010 season with the team, averaging 12.0 points, 3.7 assists, 2.7 rebounds and 1.0 steal per appearance.

On January 26, 2012, after playing twelve games for Maccabi Ashdod at the beginning of 2011–2012 season, Bradley signed with the team of Hapoel Jerusalem.