He has worked with acts such as Lady Gaga, Ariana Grande, Demi Lovato, Selena Gomez, Britney Spears, Nicki Minaj, Madonna, Charli XCX, Bon Jovi, Backstreet Boys, One Direction, Arashi, Westlife, The Saturdays, P!nk, Celine Dion, Enrique Iglesias, Tiësto, Avicii, NSYNC, 5 Seconds of Summer, Lindsay Lohan, Weezer, Måneskin, Foster the People, Taio Cruz and Loreen.
Yacoub had also a short singing career but then decided to give all his attention to writing and producing instead.
In 1998, he was approached by Max Martin, who was looking for a new production partner, and asked to join the legendary Cheiron Studios in Stockholm.
Rami's first collaboration with Martin was producing the hit "...Baby One More Time" that launched the career of Britney Spears.
[2] Following ten years of service, Rami split amicably from Maratone in early 2008 because he felt that "he needed to go [his] own way."