Rezaeian was Carlos Queiroz's first choice on the right side of the defence of the Iran men's national team in the 2018 FIFA World Cup qualification matches.

After several good performances in the 2014–15 season, Rezaeian was recognized as one of the best fullbacks in the league and was called up to the national team.

On 26 December 2015, Rezaeian scored a 30-yard free kick against Padideh in stoppage time to earn them a 2–2 draw.

Ramin made his debut on 27 July 2017 in a 3rd round Europa League qualifier against French club Olympique de Marseille.

[6] In his first match with the club, on 8 November, Ramin scored a free kick goal in his team's 5–1 loss to Al Duhail.

On 22 August 2020, Rezaeian signed a two-year contract with Qatar Stars League champion, Al-Duhail.

[8] On 12 February 2022, Rezaeian signed a contract with Persian Gulf Pro League champions Persepolis.

[9][10] On 15 July 2022, Rezaeian signed a contract with Persian Gulf Pro League side Sepahan.

[11] In December 2024 while with Esteghlal, Rezaeian was summoned by Football Federation Islamic Republic of Iran after hugging a female fan, months after goalkeeper Hossein Hosseini was also summoned by the federation and faced a suspension and fine for embracing a female fan in April 2024.