The first official game in the new building took place two-days prior as the women's squad downed Mars Hill on December 4, 1986, by a score of 65–61.

[5] Such entertainment acts as Aerosmith, Alabama, Rascal Flatts, Montgomery Gentry, Eric Church, The Band Perry, Tim Mcgraw, The Gaither Homecoming, Billy Currington, Chicago, Fabolous, Jason Aldean, Lady Antebellum, Lorrie Morgan and Nappy Roots have played at the Ramsey Center.

Other featured events include the Harlem Globetrotters, WCW Wrestling, Monster Jam, appearances by the New York City Opera, Los Angeles Ballet and the Acting Company.

Lectures from famous personalities like Pat Summitt and former presidential candidate, Bob Dole have taken place at the Ramsey Center.

[5] Bon Jovi performed at the Ramsey Center on September 23, 1986 during their Slippery When Wet Tour, and the arena is featured in the music video for the song Wanted Dead or Alive.