[2] On 28 May 1828, Sir William Hillary, President of the Isle of Man District Association of the RNIPLS, wrote to the Institution's headquarters in London, requesting that a lifeboat be placed at both Peel and Ramsey, which was duly agreed.

Following the death in 1848 of Sir William Hillary, the driving force behind the RNIPLS, and with little or no funding available, Ramsey lifeboat station effectively ceased.

An order was placed with Forrestt of Limehouse, London, who built a 33-foot (10 metre) ten-oared Self-righting lifeboat, provided by the gift of Mr James Ryder, via the Manchester Branch of the RNLI, and which was delivered to Ramsey in November 1868.

The boat, carriage and all equipment was funded by Mr and Mrs Norbury of Port Lewaigue, near Ramsey, and she was named Mary Isabella (ON 222).

Keen seafarers James and Ann Ritchie, of the Isle of Man brewing company Heron and Brearley, decided to fund a lifeboat for Ramsey.

The work included removal of the front elevation to extend the building, installing a ground source heat pump system, and internal layout reconfiguration with updated crew facilities.

[2] On the 7 November 1890. the Two Sisters was launched in rough seas to the steam dredger Walter Bibby, rescuing the 15 men on board.

For these two actions, Edward Christian Kerr, Honorary Secretary, and Robert Garett, Coxswain, were awarded the RNLI Silver Medal.

[8] The Aberdeen steam trawler Strathairlie ran aground at Skellig Bay north of Ramsey, on the night of 20 November 1941.