[1][2] During the siege of Banu Qurayza in 627, she was widowed and taken captive by the early Muslims and subsequently became a concubine [3] and according to some also a wife of Muhammad.

The 9th century Arab historian Ibn Sa'd wrote that Rayhana went on to be manumitted and subsequently married to Muhammad upon her conversion to Islam from Judaism.

The 11th-century Persian religious scholar Abu Ishaq al-Tha'labi agreed that she became one of Muhammad's wives and cited evidence that he had paid mahr for her.

The 15th-century Egyptian religious scholar Ibn Hajar makes reference to Muhammad giving Rayhanah a home upon their marriage.

[15][16] Conversely, Indian religious scholar Barakat Ahmad felt such rationale to support the notion of Rayhana and Muhammad's marriage was "meaningless" after both Jewish tribes were wiped out, in accordance with Talmudic law, following their betrayal of the early Muslims.