The name is believed by many to be based on the Sanskrit word for "snake", as well as possibly Naga, a World of Warcraft race.

There have been eleven iterations in the Naga series, not counting the redesigned versions, with release dates spanning from 2009 to 2020.

[8] The Naga 2012 supported Razer's Synapse 2.0 software allowing all the buttons to be programmed and that information to be stored online.

[12] In March 2013, after the announcement of a partnership between Razer and Riot Games, a League of Legends style Naga Hex was released,[10] with the only difference being the design and the change from a plastic to a matte surface.

The Naga Epic Chroma is wireless and also featured nineteen programmable buttons of which twelve are on the side.

[23] A left-handed version of the Naga Trinity was planned, but after an unsuccessful Kickstarter campaign, raising only US$80,000 of the desired $1.3 million, the model was cancelled.

[25] Released in August 2020, the Naga Left-Handed Edition was the first mouse in the series to have a maximum DPI of 20,000, accomplished through the implementation of the "Razer Focus+ Optical Sensor".

[42] The original Razer Naga had a positive reception, although many pointed out the obvious targeting towards MMO gamers.

[43] Ben Kuchera, of Ars Technica called it a "niche product", stating the buttons were unappealing to people who did not play MMO games.

[44] The reviewers at PC Magazine thought the Epic was expensive, but commended the mouse's attractiveness and wireless feature.

[45] Mathew McCurley of Engadget commended the long-lasting battery and the wireless capability of the mouse and stated that "if you're interested in trying something new, give it a shot.

Russell Holly of the technology site Geek.com said he would recommend it to anyone[9] and David Daw of PC World said it would be difficult to find a better gaming mouse for the same price.

Sean Buckley of Engadget disliked the Naga Hex because of its plastic surface and how the arrangement of the buttons on the side resulted in them feeling cramped.

[48] Brian Westover of PC Magazine said the hexagonal layout of the buttons made them easier to understand and use, but felt the placement of them was sub-par.

[54] Marshall Honorof's biggest criticism of the mouse was that "most people won't need one", though he continued to say that for those who do, it would work exactly as expected.

[55] Michael Crider of Digital Trends said that once the user gets used to the button layout, the actions are "quick and responsive.

Mike Epstein from PCMag noted the dropping of the modular side panels, wireless charging, and tilting scroll wheel as some downsides of the Naga X.

[59] However, reviewers at Setup.gg noted that the tradeoffs may be worth it for some gamers, particularly since dropping some of these features helped the Naga X reach the low 85-gram weight, which is light compared to competing MMO and MOBA gaming mice.