The line was transferred to Conrail on the Reading's bankruptcy in 1976.

It is now part of the Norfolk Southern Railway's Reading Line.

The East Pennsylvania Railroad was chartered on March 9, 1856, as the Reading and Lehigh Railroad, but was renamed in April 1857.

The opening of this line created a through route between Harrisburg and New York City.

[1] The East Pennsylvania continued to exist as a company, and would be merged along with the Reading into Conrail in 1976, as a result of the Reading's final bankruptcy.