John Robert Murff (April 1, 1921 – November 28, 2008) was an American relief pitcher in Major League Baseball who played from 1956 through 1957 for the Milwaukee Braves.

In part of two seasons, he posted a 2–2 record with a 4.65 ERA and three saves in 26 appearances, including two starts, giving up 26 earned runs on 56 hits and 18 walks while striking out 31 in 50+1⁄3 innings of work.

As a scout for the New York Mets, he discovered and signed future Hall of Famer pitcher Nolan Ryan and All-Star catcher Jerry Grote.

Ryan, later named president of the Texas Rangers, noted his friendship with Murff in his 1999 Hall of Fame induction speech.

In the early 1970s, Murff helped start the University of Mary Hardin-Baylor baseball program, and retired to Tyler, Texas, in 1991 after serving 34 years as a scout.