Red Sulphur Springs is an unincorporated community in Monroe County, West Virginia, United States.

Red Sulphur Springs is located on West Virginia Route 12, close to Indian Creek.

The springs were purchased by Dr. William Burke of Richmond in 1830, who built a hotel to accommodate up to 350 guests.

Among the notable guests to the springs were Chief Justice of the Supreme Court Roger Taney and Francis Scott Key.

Ownership passed to Levi Morton, who had been Vice-President of the United States under Benjamin Harrison.