The district is centered on Redlands' Atchison, Topeka and Santa Fe Railway depot, which was established in 1888.

The Pacific Electric Red Car trolley service, the Redlands Line, ran past the mainline Santa Fe station on Orange Street between 1903 and 1936.

[1] The buildings surrounding the station represent many of the important components of the city's economy, particularly the orange packing industry.

[4][5] With new ownership and a name change to Redlands Railway District LLC, the depot was restored and integrated with the adjacent Redlands–Downtown station on the Arrow commuter rail service in 2022.

This article about a property in San Bernardino County, California on the National Register of Historic Places is a stub.