It serves the northern suburb of Reservoir, in Melbourne, Victoria, Australia.

It opened on 8 October 1889, with the current station provided in 1970.

[5] Initially opened as Preston-Regent Street, the station was given its current name of Regent on 1 August 1905.

[5] Named after the locality and nearby Regent Street,[6] Regent station opened on 8 October 1889, when the Inner Circle line was extended from North Fitzroy to Reservoir.

[5] In 1967, boom barriers replaced hand gates at the Regent Street level crossing, located nearby in the up direction of the station.