He played college football for the Georgia Bulldogs and was selected by the Philadelphia Eagles in the second round of the 2005 NFL draft.

He is the cousin of former New York Jets player and a current University of West Georgia defensive backs coach, Jamie Henderson (also a Carrollton High School graduate).

[3] In 2005, his rookie season, Brown was promoted to the starting spot of suspended wide receiver Terrell Owens.

On December 16, 2007, during a game in Dallas against the rival Cowboys, Brown, after running to catch an overthrown pass, ran out of bounds and jumped in the giant Salvation Army bucket in Texas Stadium, saying he couldn't slow down in time to stop before it.

He was inactive for the first two games of the season, and completely fell behind Desean Jackson, Jeremy Maclin and Jason Avant as the team's fourth receiver.