Throughout his career, Gilliam has helped the Bills rank top 10 in the NFL in total rushing yards for every season that he has been with the team as a lead blocker.

He led the nation with four blocked kicks as a junior in 2018 and was named second-team All-Mid-American Conference.

[3] Gilliam finished his collegiate career with 18 receptions for 153 yards and three touchdowns with six blocked kicks.

[7] Gilliam made his NFL debut in the Bills' season opener against the New York Jets on September 13, 2020.

[8] The following week on September 20, 2020, Gilliam caught a one-yard touchdown pass from Josh Allen for his first career reception in a 31–28 win over the Miami Dolphins.