Sister Donna Markham, PhD, OP Regina Dominican is a college preparatory Catholic school for girls grades 9-12, located in Wilmette, Illinois.

The school subscribes to the NACAC Statement of Principles of Good Practice, and is accredited by AdvancED and the Illinois State Board of Education.

In 2012, Regina was recognized with an Edison Award Silver Medal in the category of living, working, and learning environments for its approach to education that prepares young women for global leadership.

Regina Dominican's Class of 2024 was accepted to over 146 colleges and universities across the country and was offered $19.8 million in scholarships.

Interscholastic sport teams include cheerleading, cross country running, golf, flag football, tennis, volleyball, basketball, bowling, lacrosse, soccer, softball, and track and field.