The son of an Episcopal priest,[1] Reginald Heber Weller, Jr., was born in Jefferson City, Missouri[2] or Jacksonville, Florida[1][3] on November 6, 1857.

The Russian Orthodox bishop of Alaska, Tikhon, was present as well as Antoni Kozlowski [pl] of the Polish National Catholic Church.

During his thirty-three years of active service, a longer episcopate than any other in the state at the time, Weller preached in all parts of the country.

Attendants at the Lambeth Conference in 1930 found Weller taking an active part in its deliberations and preaching in several English cathedrals.

At home or abroad, Weller was a defender of the faith, a stirring, convincing preacher of great ability, a wise pastor, generous friend, and a man of God.