Regional 2 North Midlands is an English level 6 rugby union regional league for rugby clubs in the North Midlands including sides from Leicestershire, Notts, Lincs & Derbyshire, Staffordshire and Warwickshire.

It was created following the 2022 Adult Competition Review by the Rugby Football Union (RFU).

The first-placed team at the end of season wins promotion to Regional 1 Midlands.

The league was completed with the addition of Dronfield on a level transfer from Regional 2 North East.

The league was completed by Wolverhampton and Walsall both on a level transfer from Regional 2 East Midlands.