It was previously called Regional Command West under the International Security Assistance Force (ISAF).

The new area was the former US Regional Command West consisting of Badghis, Farah, Ghor, and Herat Provinces.

On 9 October 2008 the Italian Brigadier General Paolo Serra took over command from his compatriot Brigade-General Francesco Arena.

There used to be four Provincial Reconstruction Teams (PRTs) under RC West:[1] Additional manoeuvre elements: In 2008, the Italian Army's contribution to ISAF and Operation Enduring Freedom peaked at 2,850 personnel.

Italy sent 411 troops, based on one infantry company from the 2nd Alpini Regiment tasked to protect the ISAF HQ, one engineer company, one NBC platoon, one logistic unit, as well as liaison and staff elements integrated into the operational chain of command.