The Provence-Alpes-Côte d'Azur region is a founding member of the Alps–Mediterranean Euroregion, created on 10 October 2007.

The Regional Council of Provence-Alpes-Côte d'Azur sits at the Hôtel de Région located in Marseille, 27 Place Jules-Guesde, near the Belsunce district.

The 123 seats of the Council are distributed by department: as follows:[4] The regional advisers of Provence-Alpes-Côte d'Azur wear a two-tone sash, red and gold.

In July 2017, an autonomy budget was allocated to the Regional Youth Parliament so that it could carry out its projects.

The young parliamentarians, numbering 80, represent the region with regard to the demographic weight of their training sector in the regional territory (public / private high schools, CFA of the region and students in health and social facilities), as well as with respect of the principle of parity between women and men and of territorial balance.