In 1954, the Jesuit seminary was formally named Collegium Christi Regis, The College of Christ the King.

[3] In 1976, the college moved to St. Mary Street in Downtown Toronto, close to its present site.

[3] Since 1978, by virtue of a change made in its charter, the University of Toronto has granted theology degrees conjointly with Regis College.

[3] In August 2008, Regis College agreed to move to Christie House, on the corner of Wellesley Street and Queen's Park.

It is to the south of St. Michael's College and is next to buildings that previously housed the offices of Marshall McLuhan.

As per all Jesuit institutions, it remains grounded in the concept of ad maiorem Dei gloriam, for the greater glory of God.

The Jesuit Honor Society's chapter of Alpha Sigma Nu was established at Regis College in 2000.