[2][3] In her weblog writings and appearances on radio, she describes her childhood with many references to the great talent of her father as well as the many disturbing incidents owing to his mental health issues.

Created by The Powerpuff Girls producers Craig McCracken and Lauren Faust, the show chronicles the adventures of Wander and his trusty (and cynical) steed Sylvia, as they travel the universe.

[6] As a voice actress, she has been heard in hundreds of animated television series, such as Goof Troop (as Peg Pete), Recess (as Mrs. Muriel Finster), House of Mouse and Mickey Mouse Clubhouse (as Clarabelle Cow), Bonkers (as Lucky's wife, Dyl Piquel), Pepper Ann (as title character's mom, Lydia Pearson),[7] and Kids from Room 402 (as Miss Gracie Graves the school teacher, along with several other characters that appear on the show), The Legend of Tarzan (taking over for Rosie O'Donnell as Terk in the original film), 101 Dalmatians: The Series (as Cruella De Vil), and SWAT Kats: The Radical Squadron (as Molly Mange).

She has also voiced characters in numerous films, including Antz, Who Framed Roger Rabbit,[1] Monsters University and Rob Zombie's The Haunted World of El Superbeasto.

As a musical theater actress, she starred as Ado Annie in the Columbia Artists revival of Oklahoma!, and also appeared opposite Kevin Spacey in Gypsy.

Additionally, Winchell wrote and starred as "Sheila Sands" in her show at the Roxy Theatre in Los Angeles to sold out crowds.

[citation needed] This huge viral success caught the attention of Random House, who subsequently won a bidding war to publish a book based around the Regretsy website.

In broadcasts of her KFI show, on her web diary and several other websites, Winchell revealed she and Kevin Spacey dated after high school.

[15][16] Winchell is a supporter of charities including Project Angel Food, a Los Angeles-based service providing meals for homebound people living with AIDS.