biggest hits]) is the first greatest hits compilation by the German punk band Die Toten Hosen.

The album is an apparent tribute to Johnny Thunders, as both "Wort zum Sonntag" (a tribute to punk and Johnny) and "Born to Lose" (a Heartbreakers cover recorded with Johnny) are included on this album, moreover, these songs come consecutively.

Some DTH albums (Opel-Gang, Kauf MICH!, Bis zum bitteren Ende) are in a couple of women's hands.

The second DTH best-of album shares its title with this album (Reich & sexy II: Die fetten Jahre).

Reich & sexy was certified 2× platinum in Germany during 2002.