[8] Pottery imported from Syria and Italy in the 14th–16th century CE found here, indicate that the village had a strong economy in the Mamluk period.

[7] In 1517, the village was included in the Ottoman empire with the rest of Palestine, and in the 1596 tax-records it appeared as Rayna, located in the Nahiya of Tabariyya of the Liwa Safad.

Next to the small pool that catches its flow, an ancient sarcophagus has been placed, in the form of a trough, the external parts of which tank are elegantly sculptured with whorls and garlands.

[27] In September, 14 Arab residents were reportedly killed by Israeli authorities after they had been detained near the village, brought into Reineh and accused of smuggling weapons.

[30] In 1878 Claude Reignier Conder suggested that the small spring south of Reineh, named "Ain Kana", was the location of biblical Cana.

[18][31] In Reineh, Israel, archaeologists uncovered a Jewish factory for producing stone vessels dating back to the Roman period.

The site, which includes a chalk cave functioning as both a quarry and a workshop, provides evidence that Galilean Jewish communities adhered to purity laws with the same rigor as those in Judea.

The site yielded numerous findings, such as stone cores and partially completed vessels, which are consistent with types used in Jewish ritual purification practices.

It suggests that the observance of purity laws, previously thought to be weaker in Galilee compared to Judea, was in fact similarly strict.

This is supported by the production scale of stone vessels, which were preferred over pottery due to religious beliefs about purity derived from Levitical law.