René Lodewijk Maurits Derolez (7 September 1921 – 24 March 2005) was a Belgian philologist who was Professor of English and Germanic Philology at Ghent University.

René Lodewijk Maurits Derolez was born in Aalst, Belgium on 7 September 1921.

Derolez subsequently received a scholarship from the Belgian American Educational Foundation, and studied at Harvard University from 1946 to 1948.

Delorez was elected a Member of the Royal Flemish Academy of Belgium for Science and the Arts in 1970.

His brother Albert Derolez is a medievalist and professor at the Free University of Brussels.