His father was a physician and his uncle a renowned surgeon, Léon Clément Le Fort.

He spent the last two years of the war in Versailles largely dealing with breast cancer and heart disease issues.

In 1936 he was awarded the Prix Laborie and elected president of the Société française de chirurgie et orthopédique.

To perform these experiments, Le Fort caused trauma to either attached or decapitated cadaver heads, and delivered blunt forces of varying degrees of magnitude and from different directions.

Although a common story holds that Le Fort used cannonballs to induce blunt trauma, he actually used a combination of wooden club, cast iron rod, squeezing in a vice, kicks, or simply throwing the heads against a table.