[5][4] Through the influence of his cousin the cardinal, Prie became grand-archdeacon of Bourges; archdeacon of Blois; and dean of the Église Saint-Hilaire-le-Grand.
[4] On 8 January 1499, in Nantes, he signed the marriage contract of Louis XII of France and Anne of Brittany.
[4] Cardinal Georges d'Amboise, who was then the papal legate to France, presented him with the red hat on 5 August 1507 in the church of the Dominicans in Lyon.
[4] During the War of the League of Cambrai, he accompanied Louis XII in his expedition against Milan in October 1510, in direct violation of the pope's orders.
[4] Pope Julius II deposed him as a cardinal on 24 October 1511 and excommunicated him for his role in organizing a schismatic council at Pisa that opened on 1 November 1511.
[4] On 10 January 1512 he wrote to the University of Paris in opposition to writings by Thomas Cajetan attacking Jean Gerson.