Renee has been responsible for numerous crimes, including the assassination of a Turkish interior minister, the deaths of three CIA agents in Serbia, an attack on a CIA listening post in Turkey, the theft of a cryogenic container from the Department of Special Research, and the infiltration of a US Army facility in Frankfurt, Germany.

In the episode "The Horizon", she assisted Jack Bristow (albeit unsuccessfully) in trying to rescue Sydney from her Prophet Five kidnappers.

In the episode "Maternal Instinct", she worked with Marcus Dixon to obtain information regarding a classified SD-6 mission.

In the episode "30 Seconds", Sydney offered her a position at APO, but Renée refused because she preferred to work according to her own schedule and she trusted very few people.

A subsequent autopsy of Renée recovered an incomplete microchip, hidden in her body for at least thirty years.

The completed microchip revealed the location of a nuclear fallout shelter containing research on Prophet Five compiled by Bill Vaughn and Luc Goursaud.