Born in Bellflower, California to Andrés García and Dolores Cuéllar, Renae attended Los Altos High School in Hacienda Heights, California where she was a three-year letterwinner and three time all-conference, all-city, all-district, all-region, and Offensive Player of the Year.

As a junior, Cuéllar scored six goals and provided three assists in the first six games of the season, before suffering a season-ending knee injury.

Cuéllar led the Sooners with 26 points from a team-high 12 goals, which ranked as the third-most in a single season in school history.

[6] In 2013, as part of the NWSL Player Allocation, Cuéllar joined FC Kansas City in the new National Women's Soccer League.

She missed two games after spraining her knee and ankle during a match against the Portland Thorns FC after being tackled by defender, Rachel Buehler.

[11] On 1 July 2013, FCKC traded Cuéllar to the Seattle Reign FC in exchange for Teresa Noyola, a second round pick in the 2014 NWSL College Draft and rights to unsigned player, Nikki Krzysik.

She resumed soccer training with men's club Las Vegas Lights FC, where her husband Carlos Alvarez was on the roster.

She scored a goal in Mexico's 3–3 draw against Japan and netted the game winner in the 62nd minute in a 1–0 victory over England.

When Mexico embarrassingly failed to qualify for the 2019 FIFA Women's World Cup in France, Cuéllar criticized the team's management for not selecting her, alleging that she'd been left out due to her recent childbirth.