[9] He attended university in order to become a lawyer, but dropped out after two years to pursue a career in mixed martial arts.

[18] Moicano was expected to face Mike De La Torre on September 24, 2016, at UFC Fight Night 95,[19] but was forced to pull out with injury and was replaced on short notice by Godofredo Pepey.

[25] After the fight with Ortega, Moicano moved from Brazil to United States in order to train at the American Top Team.

[35] Moicano faced Damir Hadžović in a lightweight bout on March 14, 2020, at UFC Fight Night 170.

[39] Two weeks later, it was reported that Moicano was scheduled to face Rafael Fiziev on November 28, 2020, at UFC on ESPN: Smith vs.

[53] Despite having his face cut open in the second round, Moicano had a significant amount of top-position control time which helped him win the bout by unanimous decision.

[55] After being knocked down at the end of the first round, Moicano rallied back and won the bout by technical knockout as a result of ground-and-pound.

[56] Moicano faced Benoît Saint Denis in the main event on September 28, 2024 at UFC Fight Night 243.

[57] He won the fight by technical knockout due to doctor stoppage at the end of the second round as a result of damage done to Saint Denis' right eye.

[59] A day before the event, an injury suffered by title challenger Arman Tsarukyan forced him to pull out of the fight.

Moicano ended up replacing Tsarukyan and challenged Lightweight Champion Islam Makhachev for the title.

[61] Moicano defeated Chase Hooper via unanimous decision at Fury Pro Grappling 3 on December 30, 2021.

[62] Moicano faced Cristian Guzman in the co-main event of UFC Fight Pass Invitational 7 on May 15, 2024.

[68] His advocacy for Bitcoin was highlighted by Fox Business in 2024, where Moicano framed cryptocurrency as a safeguard against financial instability.