Multinational and publicly traded corporations in the Research Park include: ADM, Abbott Laboratories, AbbVie, Ameren, AGCO, bp, Bayer, Brunswick, Capital One, Cargill, Caterpillar, CME Group, Corteva, Deere & Company, Kohler, Littelfuse, Motorola Solutions, Nutrien Ag Solutions, NVIDIA, Riverbed, Rivian, State Farm, Synchrony, and Yahoo (Verizon Media Group).

EnterpriseWorks, the Research Park's 43,000-square-foot business incubator for early-stage tech firms, is operated by the University of Illinois to help launch successful startup companies.

[2] The Research Park Master Plan, adopted in September 2018 by the University of Illinois Board of Trustees, aims to double its size and continue attracting more companies, employees, and private development.

The award-winning incubator provides free counseling services to technology entrepreneurs and facilities such as laboratories, offices, conference rooms, kitchen, and co-working space.

[4] Research Park and the EnterpriseWorks Incubator hold educational, training, social, and networking events to facilitate a community feel while providing a place where the newest startups have the opportunity to develop relationships with established national and international corporations.