The film stars Cillian Murphy, Jamie Bell, and Thandiwe Newton as three people isolated from the rest of the world on a remote island.

After recently suffering a miscarriage, Kate's relationship with Martin has become tense, and in an effort to rekindle their marriage they decide on a return visit to the island.

He tells Martin and Kate that there has been an outbreak of an airborne disease, Argromoto Flu, codenamed R1N16, that started in South America and has spread over the entire world in just a few weeks.

The disease is incurable and highly contagious, attacking the respiratory system and causing victims to choke on blood with a 100% fatality rate.

As she attempts to leave the island in the boat with Martin’s body, a military helicopter flies over and she is killed by a sniper who shoots her in the head.

[4] Peter Bradshaw of The Guardian rated it 3/5 stars and called it "a neat, tense thriller from a first time director that provides a decent role for Jamie Bell".

[5] John Anderson of Variety wrote, "A potential menage a trois of terror is served up as rather weak tea in Retreat, which fails to make its alleged suspense, thrills or even its mist-enshrouded landscapes particularly plausible.

[9] David Nussair of Reel Film Reviews wrote that "Retreat inevitably (and lamentably) establishes itself as a generic and hopelessly uninvolving thriller that grows more and more tedious as it progresses.