Rex Colman Brothers (born December 18, 1987) is an American former professional baseball pitcher.

He also played in Major League Baseball (MLB) for the Atlanta Braves and Chicago Cubs.

He finished the season with a 1–2 win–loss record, a 2.88 earned run average (ERA), and 59 strikeouts in 40+2⁄3 innings in the majors.

[9] On November 25, 2015, Brothers was traded to the Chicago Cubs for minor league pitcher Wander Cabrera.

[11] On February 3, 2017, after not pitching in baseball in 2016, Brothers signed a minor league contract with the Atlanta Braves.

[17] In 36 appearances split between the Triple–A Scranton/Wilkes-Barre RailRiders and Low–A Staten Island Yankees, he accumulated a 4.62 ERA with 88 strikeouts across 48+2⁄3 innings pitched.

[18] On December 18, 2019, Brothers signed a minor league contract with the Chicago Cubs.

[22] In 57 games for the Cubs, Brothers posted a 5.26 ERA/4.87 FIP, struck out 75 batters, and earned one save across 53 innings.

Brothers struggled immensely to the tune of a 17.36 ERA in 7 appearances for Nashville before he was released by the Brewers on May 3, 2022.