Rhein-Hunsrück-Kreis is a district (German: Kreis) in the middle of Rhineland-Palatinate, Germany.

The neighbouring districts are (from north clockwise) Mayen-Koblenz, Rhein-Lahn, Mainz-Bingen, Bad Kreuznach, Birkenfeld, Bernkastel-Wittlich, Cochem-Zell.

In 2014 it was expanded with the municipalities Lahr, Mörsdorf and Zilshausen, previously part of Cochem-Zell.

In 1962, Simmern began a friendship pact with the French region Bourgogne, which was continued after the merging with the St. Goar.

In 1985 a partnership was started with the district Nyaruguru (at that time called the municipality Rwamiko) in Rwanda, as part of the partnership of the Rhineland-Palatinate region with Rwanda.