[3] Rhinella icterica is the most common toad species found in southeastern Brazil and preys on the yellow scorpion (Tityus serrulatus).

[5] This may be due to Rhinella icterica toxic secretion (RITS) that ultimately acts as a concentration independent irreversible neuromuscular blockade.

There are cutaneous glands that are scattered all over the body of amphibians that aide in respirating, water balance, and chemical defense.

The mucous cells in this toad species also produces neutral glycoproteins that are rich in galactose, galactosamine, and glucosamine residues.

This is similar to other toad species whose mucous layer that serves to protect the surface of the stomach and is formed by neutral glycoconjugates.

[8] Rhinella icterica is found in the Atlantic Forest, spanning southeastern and southern Brazil, eastern Paraguay, and in the Misiones and Corrientes provinces of Argentina.

However, due to more recent deforestation and the building of new roads, there has been a decrease in the ability of toads to access water which is necessary for their breeding.

Because of this, the population of Rhinella icterica is gradually decreasing, causing an increase in the number of scorpions found in this area.