The album features Pan-African artists such as Nasty C, Larry Gaaga, Umu Obiligbo, Locko, Tekno, Tellaman, Sha Sha, Oxlade, Alpha P, TMXO, DJ Arafat, Prince Kaybee, Msaki, Tiwa Savage, Th&o., Diamond Platnumz, Morgan Heritage, Toofan, Fally Ipupa, BONJ, Gemini Major, Anatii, De Mthuda, Njelic, and Ricky Tyler, as well as appearances from Ari Lennox.

On February 12, 2021, Def Jam revealed[2] the CEO of Universal Music South Africa, Sipho Dlamini, as the curator and executive producer of Rhythms of Zamunda.

The Pan-African project was inspired by the film, with lead single "Black and White" by Nasty C and Ari Lennox.

On March 10, 2021, National Public Radio released a Tiny Desk show, titled Coming 2 America, Sounds Of Zamunda: Tiny Desk (Home) Concert,[3] a live performance from Nasty C, Lennox, Locko, Ricky Tyler, Alpha P, Prince Kaybee, Msaki, and Toofan.

In February 2021, Sipho Dlamini said, "We wanted to bring our knowledge of the music from the continent that is coming up and affecting the youth globally — it's not just Afrobeats.