He was the eldest son of Piers Edgcumbe of Mount Edgcumbe House and Cotehele, Calstock, Cornwall, and his wife, Mary, daughter of Sir John Glanville of Broad Hinton, Wiltshire.
[1] He had married Anne, daughter of Edward Montagu, 1st Earl of Sandwich and Jemima Crewe.
They also had a daughter Anne who married Henry Pyne, a wealthy landowner of an established County Cork family.
Her mother – the much loved "my lady" of Samuel Pepys – spent her last years at Mount Edgecumbe and is buried there.
In his Tangier Journal Pepys records a visit to Lady Edgcumbe on 22 August 1679: "She received me extremely kindly.