(2001) and Elvis (2022), the ABC series Rake (2010–2018), and the action films Mission: Impossible 2 (2000), The League of Extraordinary Gentlemen (2003), and Van Helsing (2004).

[1] Roxburgh studied economics at the Australian National University in Canberra,[2][1] where he resided at Garran Hall and graduated with a B.Ec.

[1] He came to public attention for his portrayal of New South Wales Police Force detective Roger Rogerson in the 1995 television miniseries Blue Murder.

[11] In 2015, Roxburgh appeared in Andrew Upton's adaptation of Chekhov's play Platonov, titled The Present, for the STC.

It was directed by John Crowley and featured Cate Blanchett, Jacqueline McKenzie, Marshall Napier, and Toby Schmitz.

[12] That production moved in 2016/17 to the Ethel Barrymore Theatre in New York City for the Broadway debut of Roxburgh and the rest of the cast.

[19] Roxburgh wrote and illustrated the well-received, 240-page children's adventure fiction title, Artie and the Grime Wave, published by Allen & Unwin in October 2016 (ISBN 9781760292140).

[1] He married Italian-born opera singer, actress, blogger, cookbook author, and television cookery show personality Silvia Colloca in 2004.