[2] At the age of 20 in 1604 Strode was elected Member of Parliament for Bere Alston in Devon, on his father's interest, and was knighted a month later.
Sir John Strode's widow, Lady Ann, was struck dead by a Parliamentarian soldier while defending her home during the Civil War.
Later ramblings suggest that Strode had become mentally unstable and he was imprisoned in the Fleet prison with debts of £200.
He wrote long letters to Oliver Cromwell setting out his grievances and he was eventually released as being of unsound mind.
By her he had eight daughters and one son,[6] William Strode (1614–1676), MP for Plympton, who inherited Newnham from his father.