Vito began his professional career in 1971 upon moving to Los Angeles and subsequently joining Delaney & Bonnie & Friends, also working with Todd Rundgren and Derek & The Dominoes’ Bobby Whitlock.

He played the slide guitar solo on the Bob Seger song (and Chevy truck TV commercial), "Like a Rock".

Vito also recorded and/ or performed with John Mayall, Jackson Browne, Little Richard, Roger McGuinn, Roy Orbison, Dobie Gray, John Fogerty, Stevie Nicks, Albert Collins, Dolly Parton, Maria Muldaur, Bob Seger, and many others.

[4] He also participated in an all-star tribute to Fleetwood Mac founder Peter Green at the London Palladium in February 2020.

Billed as "Mick Fleetwood & Friends," the show highlighted Vito's guitar and vocals alongside of Billy Gibbons, Pete Townshend, David Gilmour, Jonny Lang, John Mayall, Christine McVie, Bill Wyman, Jeremy Spencer and more.

[6] He first appeared on the band's 1988 Greatest Hits album, which featured Vito's playing on "As Long as You Follow" and "No Questions Asked", which were recorded specifically for the compilation.