Through his academic studies he achieved a doctoral degree in Business Economics at the University of Federico II in Naples, and a diploma at the Università popolare dello spettacolo, a three years theater and arts school.
In 1994 Rino Piccolo experienced the Actors Studio under such moderators as Sidney Pollack, Barry Primus, Anthony Franciosa, Martin Landau, Mark Rydell and Shelley Winters.
In 2001 Piccolo was appointed as Italian Film Commission's and cinema delegate to present to the Indian Government the new national agreement between the two countries and promote new opportunities of international development.
In 2013 has presented the new Region of Lazio 15 million euro "Audiovisual fund" to the Spanish film Industry at the Italian Embassy in Madrid.
Throughout the years he has collaborated on international film projects such as: The Borgias, Angels and Demons, Maradona by Kusturica, The man from U.N.C.L.E., Spectre, Zoolander 2, 7 minuti and many others.