The cast includes Scott Cohen, Christopher Walken, Paul Giamatti, Karen Allen, Burgess Meredith (in his final performance before his death the following year), David Patrick Kelly, Ossie Davis, and John Rhys-Davies.

A limited number of the clues and puzzles, plus a single line of dialogue in the ending, change according to the villain's identity.

Ripper is the second of the three Take-Two developed full-motion video-based adventure games, the other two being Hell: A Cyberpunk Thriller and Black Dahlia.

Along with the police (whose investigation is headed by Detective Vincent Magnotta), Quinlan is seeking The Ripper's true identity.

Assistance from a pathologist named Vic Farley reveals that The Ripper's murders were done by placing a code into a victim's brain while in cyberspace that caused their internal body pressure to rise to a point of explosion, which Farley experiences immediately after providing his explanation.

Quinlan also finds a cyberspace weapon developed by a murdered cyber-architect named Hamilton Wofford, designed specifically to kill The Ripper inside a virtual recreation of the historic Whitechapel district of London, where the Jack the Ripper murders took place.

[16] Arinn Dembo of CNET Gamecenter wrote, "[S]low sales, unfortunately, quickly knocked [Ripper] off retail shelves.

He specifically criticized that the characters "are so overdone it's just plain funny" and the first-person sequences can't be bypassed, forcing the player to watch the same graphics every time they backtrack.

[4] Jeff Sengstack of NewMedia magazine wrote that Ripper "meets, even exceeds, its pre-release hype", and summarized it as "an engaging horror mystery with immense depth."